Transcript quotes from Dr. Coffin about 2010 CROI

CROI = Conference on retroviruses and opportunistic infections

Dr John Coffin - Recent XMRV remarks at CRIO 2010:

Coffin: "That new virus is called XMRV. It was first described in some cases of, associated with some cases of prostate cancer about three or four years ago but it really burst onto the scene last fall when a study reporting that it was associated with many cases of in a cohort of patients with chronic fatigue syndrome.  The study reported detecting the virus in about two-thirds of the patients in this particular cohort.  Potentially a very exciting result because for any number of reasons; one is because chronic fatigue syndrome has been a very mysterious disease, the other is that the association of prostate cancer was a little unsatisfying in some ways -- that I can get into if you want. But this is very clear evidence that this virus was in fact infecting people and also that in both the prostate cancer study and this one there was a significant fraction of normal controls, uninfected people showed, also showed signs of infection with this virus.  The number being on the order of 4% in the two studies, which if you take that over the whole population of the United States or the whole population of the world that actually turns out to be a very large number of infected individuals. More, much more, for example in the United States than the total number of HIV infected individuals, and so the possibility of this virus might be associated with this or perhaps other kinds of diseases is a very real one and one that really needs to be investigated and nailed down."

 

Complete transcript and video can be found at:

http://www.medpagetoday.com/clinical-context/HIVAIDS/19456

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